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Microbiology and Infectious Disease

Microbes rule our world. Faculty in BMB study bacteria, archaea, viruses, and eukaryotic parasites, and investigate how these organisms impact everything from the environment to human health.

Dr. Babitzke's Research Interest:  Regulation of gene expression

by RNA structure and RNA-binding proteins.  

Dr. Bisanz's Research Interest: The structure and function

of the microbiome and its impacts on health and disease.  

Dr. Booker's Research Interest:  Elucidating the chemical

mechanisms by which enzymes containing iron-sulfur clusters

catalyze chemical reactions.   

Academy Professor, Ernest C. Pollard Professor Emeritus of Biotechnology, and Professor Emeritus of Biochemistry and Molecular Biology

Dr. Bryant's Research Interest:  Genomics, structural and

functional relationships, metabolism, physiology and ecology

of chlorophototrophic bacteria.   

Dr. Hafenstein's Research Interest:  A structural approach to

learn more about viral infectivity, tropism, evolution and


Dr. Jose's Research Interest: The understanding of the molecular

mechanisms involved in the replication and assembly of

flaviviruses and alphaviruses. 

Dr. Keiler's Research Interest:  Protein quality control, ribosome

rescue, and new antibiotics.   

Dr. Lindner's Research Interest:  The coupling of molecular

parasitology and structural biology to study the malaria


Distinguished Professor of Biochemistry and Molecular Biology and of Chemistry

Dr. Llinás' Research Interest:  The combination of tools from

functional genomics, molecular biology, computational biology,

biochemistry, and metabolomics to understand the fundamental

molecular mechanisms underlying the development of this


Associate Professor of Biochemistry and Molecular Biology

Dr. Miyashiro's Research Interest: We use microbial genetics,

biochemistry, and cell biology approaches to determine the

molecular mechanisms that enable bacteria to establish

symbiosis with a eukaryotic host.  The model system is the

symbiosis formed between the bioluminescent bacterium Vibrio

and the Hawaiian bobtail squid Euprymna scolopes

Our primary interests in this system include quorum sensing,

contact-dependent killing mechanisms, and sulfur metabolism.   

Dr. Meredith's Research Interest:  Bacterial cell envelope


Professor of Biochemistry and Molecular Biology

Dr. Murakami's Research Interest:  We apply cryo-EM and X-ray

crystallography techniques to reveal three-dimensional structures 

of DNA and RNA polymerases for elucidating the mechanisms of

DNA replication and RNA transcription.   

Dr. Patterson's Research Interest:  Understanding the host-

metabolite-microbiota communication network‚ specifically

how the manipulation of gut microbiota by diet and/or

xenobiotics impacts host metabolites (e.g., bile acids, short

chain fatty acids), their metabolism, and how these co-

metabolites interact with host ligand-activated transcription


Dr. Paulson's Research Interest:  The mechanism of tissue

regeneration using the response to anemia as a model system.   

Associate Professor of Biology and Biochemistry and Molecular Biology

Dr. Szpara's Research Interest:  Understanding the consequences

of HSV latency for the neurons that harbor the HSV pathogen

and the search for improved therapeutics using a combination

of virology, neurobiology,  next generation sequencing

technologies, and bioinformatics.    

Associate Professor of Biochemistry and Molecular Biology, and of Chemistry

Dr. Weinert's Research Interest:  The understanding of how

the globin coupled sensor protein family senses oxygen and

transmits the binding signal into downstream events.