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Biochemistry and Enzymology

Dr. Armache's Research Interest:  Mechanisms and functions of

ATP-dependent chromatin remodeling complexes and their place

in genome regulation

Dr. Anand's Research Interest: Uncovering dynamics of cellular

macromolecular assemblies.  

Professor of Biochemistry and Molecular Biology and of Physics

Dr. Bai's Research Interest:  Chromatin structure and its role in

gene regulation. 

Dr. Bevilacqua's Research Interest:  Attaining a molecular level

understanding of RNA in biology.  

Dr. Boal's Research Interest:  The study of the structural

differences between members of largemetalloenzyme

superfamilies that share common features but promote

different reactionsor use distinct cofactors.  

Dr. Bollinger's Research Interest:  The understanding of the

relationship between the structures and catalytic mechanisms of

enzymes that employ such clusters, and to elucidate the

biochemical mechanisms by which the proteins acquire their


Dr. Booker's Research Interest:  Elucidating the chemical

mechanisms by which enzymes containing iron-sulfur clusters

catalyze chemical reactions.  

Academy Professor, Ernest C. Pollard Professor Emeritus of Biotechnology, and Professor Emeritus of Biochemistry and Molecular Biology

Dr. Bryant's Research Interest:  Genomics, structural and

functional relationships, metabolism, physiology and ecology

of chlorophototrophic bacteria.  

Professor Emeritus of Biochemistry and Molecular Biology

Dr. Ferry's Research Interest:  The study the enzymology and

molecular biology of anaerobic microbes from the Archaea


Emeritus, Professor of Biochemistry and Biophysics, and Chemistry

Dr. Golbeck's Research Interest:  Biophysical studies of electron

transfer mechanisms in photosynthetic prokaryotes.  

Associate Department Head for Graduate Education and Professor of Biochemistry and Molecular Biology

Dr. Gu's Research Interest:  The utilization of biochemical,

molecular genetics, and spectroscopic approaches to

decipher mechanisms of cellulose biosynthesis. 

Dr. Hanna-Rose's Research Interest:  We use genetic and

metabolomics approaches in C. elegans to model inborn errors

of metabolism and probe the molecular links between metabolic

perturbations and animal behavior and physiology.  

Dr. Keiler's Research Interest:  Protein quality control, ribosome

rescue, and new antibiotics.  

Dr. Kreb's Research Interest:  The elucidation of the reaction

mechanisms by which mono- and dinuclear non-heme-iron

enzymes activate dioxygen (O2) for a wide variety of oxidative


Professor of Biology and Biochemistry and Molecular Biology

   Dr. Lai's Research Interest:  Growth Control and Cancer Genetics.  

Dr. Lesk's Research Interest:  Computational analysis of protein

structure, function, genomics and evolution.  

Distinguished Professor of Biochemistry and Molecular Biology and of Chemistry

Dr. Llinás' Research Interest:  The combination of tools from

functional genomics, molecular biology, computational biology,

biochemistry, and metabolomics to understand the fundamental

molecular mechanisms underlying the development of this


Assistant Professor of Biochemistry and Molecular Biology, and Dorothy Foehr Huck and J. Lloyd Huck Early Career Chair in Biochemistry and Molecular Biology

Dr. Melanie McReynolds' Research Interest:  The understanding

of the biochemistry behind aging, and its intersection with stress, with

the long-term goal of identifying strategies that promote healthier aging. 

Dr. Meredith's Research Interest:  Bacterial cell envelope


Professor of Biochemistry and Molecular Biology

Dr. Murakami's Research Interest:  We apply cryo-EM and X-ray

crystallography techniques to reveal three-dimensional structures 

of DNA and RNA polymerases for elucidating the mechanisms of

DNA replication and RNA transcription.  

Dr. Okafor's Research Interest:  The structural mechanisms of

signaling and regulation in protein complexes.  

Dr. Patterson's Research Interest:  Understanding the host-

metabolite-microbiota communication network‚ specifically

how the manipulation of gut microbiota by diet and/or

xenobiotics impacts host metabolites (e.g., bile acids, short

chain fatty acids), their metabolism, and how these co-

metabolites interact with host ligand-activated transcription


H. Thomas & Dorothy Willits Hallowell Chair of Agricultural Sciences and Director of the Center for Molecular Toxicology and Carcinogenesis

Dr. Perdew's Research Interest:  The biochemical pathway of

AHR activation and characterized species difference in AHR

mediated transcriptional activation of target genes.  

Dr. Peter's Research Interest:  The role of the peroxisome

proliferator-activated receptors (PPARs) in the regulation

of homeostasis, toxicology and carcinogenesis.  

Dr. Reese's Research Interest:  Stress-induced gene expression

and UV resistance pathways, Regulation of mRNAs from birth to

death during stress responses, Targeted protein degradation

during transcriptional stress and How RNA Polymerase II contends

with barriers throughout the genome.  

Dr. Roy's Research Interest:  Forensic DNA analysis using

massively parallel sequencing and short tandem repeat

technology, trace evidence, fingerprints.  

Dr. Showalter's Research Interest:  The use of solution

nuclear magnetic resonance (NMR) spectroscopy, in combination

with thermodynamic analysis, chemical biology, and cellular

assays to advance understanding of protein function.  

Associate Professor of Biology and Biochemistry and Molecular Biology

Dr. Szpara's Research Interest:  Understanding the consequences

of HSV latency for the neurons that harbor the HSV pathogen

and the search for improved therapeutics using a combination

of virology, neurobiology,  next generation sequencing

technologies, and bioinformatics.  

Dr. Tan's Research Interest:  The understanding of how genes

are regulated by combining genetic, biochemical and structural


Associate Professor of Biochemistry and Molecular Biology, and of Chemistry

Dr. Weinert's Research Interest:  The understanding of how

the globin coupled sensor protein family senses oxygen and

transmits the binding signal into downstream events.  

Assistant Professor of Chemistry and of Biochemistry and Molecular Biology